Microbiome in Multiple Sclerosis: Where Are We, What We Know and Do Not Know
Marina Boziki, Evangelia Kesidou, Paschalis Theotokis, Alexios‐Fotios A. Mentis, Eleni Karafoulidou, Mikhail Melnikov, A A Sviridova, Vladimir Rogovski, Alexey Boyко, Nikolaos Grigoriadis
Abstract
An increase of multiple sclerosis (MS) incidence has been reported during the last decade, and this may be connected to environmental factors. This review article aims to encapsulate the current advances targeting the study of the gut-brain axis, which mediates the communication between the central nervous system and the gut microbiome. Clinical data arising from many research studies, which have assessed the effects of administered disease-modifying treatments in MS patients to the gut microbiome, are also recapitulated.
Topics & Concepts
Multiple sclerosisMicrobiomeGut microbiomeDiseaseCentral nervous systemMedicineNeed to knowNeuroscienceBioinformaticsBiologyImmunologyPathologyComputer scienceComputer securityGut microbiota and healthMultiple Sclerosis Research StudiesCystic Fibrosis Research Advances