Litcius/Paper detail

Hydroxyl radical is a significant player in oxidative DNA damage<i>in vivo</i>

Barry Halliwell, Amitava Adhikary, M. Dingfelder, Miral Dizdaroğlu

2021Chemical Society Reviews327 citationsDOIOpen Access PDF

Abstract

) plays the key role. We examine these claims and summarize the evidence that ˙OH does play a key role as an important member of the reactive oxygen species (ROS) in vivo.

Topics & Concepts

Hydroxyl radicalIn vivoChemistryOxidative phosphorylationOxidative damageReactive oxygen speciesDNA damageDNABiophysicsBiochemistryPhotochemistryRadicalOxidative stressBiologyGeneticsBioactive Compounds and Antitumor AgentsGenomics, phytochemicals, and oxidative stressFree Radicals and Antioxidants