Simple Mix-and-Read Assay with Multiple Cyclic Enzymatic Repairing Amplification for Rapid and Sensitive Detection of DNA Glycosylase
Juan Hu, Wen Liu, Jufeng Wang, Jian‐Ge Qiu, Chun‐yang Zhang
Abstract
U/μL, and it can be applied for the screening of inhibitors and the monitoring of cellular hOGG1 activity at the single-cell level, providing an adaptive and flexible tool for clinical diagnosis and drug discovery.
Topics & Concepts
ChemistryDNA glycosylaseDNAEnzymeChromatographyBiochemistryDNA repairDNA Repair MechanismsCRISPR and Genetic EngineeringMolecular Biology Techniques and Applications