Creatine attenuates seizure severity, anxiety and depressive-like behaviors in pentylenetetrazole kindled mice
Emmanuel Oshiogwe Okwuofu, Gbenga Emmanuel Ogundepo, Abigail M. Akhigbemen, Akinpelu Lateef Abiola, Raymond I. Ozolua, Ighodaro Igbe, Ononiwu Chinazamoku
Topics & Concepts
MalondialdehydeConvulsionEpilepsyLipid peroxidationElevated plus mazeTail suspension testCreatineInternal medicineSuperoxide dismutaseAnxietyMedicineEndocrinologyPsychologyAnesthesiaOxidative stressPharmacologyBehavioural despair testHippocampusAntidepressantPsychiatryNeuroscience and Neuropharmacology ResearchDiet and metabolism studiesTreatment of Major Depression