Catalytically Active Peptide–Gold Nanoparticle Conjugates: Prospecting for Artificial Enzymes
Dorian J. Mikolajczak, A. Berger, Beate Koksch
Abstract
The self-assembly of peptides onto the surface of gold nanoparticles has emerged as a promising strategy towards the creation of artificial enzymes. The resulting high local peptide density surrounding the nanoparticle leads to cooperative and synergistic effects, which result in rate accelerations and distinct catalytic properties compared to the unconjugated peptide. This Minireview summarizes contributions to and progress made in the field of catalytically active peptide-gold nanoparticle conjugates. The origin of distinct properties, as well as potential applications, are also discussed.
Topics & Concepts
Colloidal goldPeptideNanoparticleConjugateEnzymeNanotechnologyChemistryArtificial enzymeCombinatorial chemistryMaterials scienceBiophysicsBiochemistryBiologyMathematical analysisMathematicsNanocluster Synthesis and ApplicationsAdvanced Nanomaterials in CatalysisAdvanced biosensing and bioanalysis techniques