A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice
Yang Yang, Natacha Jn-Simon, Yonghan He, Chunbao Sun, Peiyi Zhang, Wanyi Hu, Tian Tian, Huadong Zeng, Sreenivasulu Basha, Araceli S. Huerta, Lu‐Zhe Sun, Xiao‐Ming Yin, Robert Hromas, Guangrong Zheng, Liya Pi, Daohong Zhou
Topics & Concepts
Hepatocellular carcinomaCancer researchCarcinomaInternal medicineMedicineProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments