MRI-Based Prostate-Specific Antigen Density Predicts Gleason Score Upgrade in an Active Surveillance Cohort
Samuel L. Washington, Avi Baskin, Niloufar Ameli, Hao G. Nguyen, Antonio C. Westphalen, Katsuto Shinohara, Peter R. Carroll
Abstract
MRI PSAD was significantly associated with Gleason score upgrading on subsequent biopsy for men initially diagnosed with Gleason 3+3 disease. Although this result is intuitive, to our knowledge it has not been previously shown. As MRI utilization increases, MRI PSAD can aid in risk stratification for men managed with AS.
Topics & Concepts
MedicineProstate-specific antigenCohortUpgradeProstateNuclear medicineInternal medicineCancerOperating systemComputer scienceProstate Cancer Diagnosis and TreatmentProstate Cancer Treatment and ResearchCardiac Imaging and Diagnostics