Litcius/Paper detail

Not a Tumor-Nonspecific Orbital Inflammation

James A. Garrity

2021Journal of Neurological Surgery Part B Skull Base15 citationsDOIOpen Access PDF

Abstract

Abstract Objective This study was aimed to illustrate the features and complexities of nonspecific orbital inflammation via discussion of two representative cases. Design Present study is a retrospective case review. Setting The study was conducted at a tertiary care medical center. Participants Two patients with nonspecific orbital inflammation were participants of this retrospective study. Main Outcome Measures Outcome of the study was disease-free patients and off all medications. Results At follow-up, both patients are disease free and off all medications. Conclusion Surgery plays a diagnostic and therapeutic role. While the clinical subtype is important for differential diagnosis and symptomatic treatment, the histologic subtype is similarly important. For inflammatory dacryoadenitis, surgery can be therapeutic. For extensive granulomatosis with polyangiitis, debulking surgery may allow better penetration of medications, especially rituximab.

Topics & Concepts

MedicineGranulomatosis with polyangiitisRetrospective cohort studyRituximabDebulkingDiseaseTertiary careSurgeryDacryoadenitisDifferential diagnosisInternal medicineVasculitisPathologyLymphomaOvarian cancerCancerIgG4-Related and Inflammatory DiseasesAutoimmune and Inflammatory DisordersOtitis Media and Relapsing Polychondritis