Convallatoxin promotes apoptosis and inhibits proliferation and angiogenesis through crosstalk between JAK2/STAT3 (T705) and mTOR/STAT3 (S727) signaling pathways in colorectal cancer
Zhi Hong Zhang, Ming Yue Li, Zhe Wang, Hong Xiang Zuo, Jing Ying Wang, Yue Xing, Cheng Hua Jin, Guanghua Xu, Lian Xun Piao, Hongxin Piao, Juan Ma, Xuejun Jin
Topics & Concepts
CrosstalkSTAT3PI3K/AKT/mTOR pathwayAngiogenesisCancer researchApoptosisSignal transductionColorectal cancerChemistryCell biologyMedicineCancerBiologyBiochemistryInternal medicinePhysicsOpticsCytokine Signaling Pathways and InteractionsMedicinal plant effects and applicationsSesquiterpenes and Asteraceae Studies