Targeting PD-L1 and TIGIT could restore intratumoral CD8 T cell function in human colorectal cancer
Marion Thibaudin, Emeric Limagne, Léa Hampe, Elise Ballot, Caroline Truntzer, François Ghiringhelli
Topics & Concepts
AtezolizumabTIGITImmune systemColorectal cancerImmunotherapyMedicineCancer researchTumor-infiltrating lymphocytesCD8T cellEx vivoOncologyImmunologyInternal medicineCancerIn vivoBiologyPembrolizumabBiotechnologyCancer Immunotherapy and BiomarkersImmune Cell Function and InteractionCAR-T cell therapy research