POST-TRAUMATIC STRESS DISORDER, INSOMNIA, HEART RATE VARIABILITY AND METABOLIC SYNDROME (NARRATIVE REVIEW)
A.A. Serhiyenko, Myroslav Baitsar, V.B. Sehin, Ludmila Serhiyenko, Vitaliy Kuznets, Victoria Serhiyenko
Abstract
This narrative review was aimed to analyze the scientific data about the association of post-traumatic stress disorder, insomnia, obstructive sleep apnea syndrome, dyssomnias, heart rate variability, metabolic syndrome, type 2 diabetes mellitus, and cardiovascular autonomic neuropathy, along with potential pathophysiological mechanisms underlying these associations. The results of experimental, cohort, prospective, and randomized clinical studies provide evidence of common pathogenetic pathways contributing to their development. Searches were conducted in Scopus, Science Direct (from Elsevier), EBSCO, and PubMed databases, including the Medline databases. Additionally, a manual search of publication bibliographies was undertaken to uncover research outcomes not accessible through online searches.