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Reversible inhibition of the oxidase-like activity of Fe single-atom nanozymes for drug detection

Weiwei Wu, Liang Huang, Xinyang Zhu, Jinxing Chen, Daiyong Chao, Minghua Li, Shuangli Wu, Shaojun Dong

2022Chemical Science91 citationsDOIOpen Access PDF

Abstract

and ) of 0.431 mM and 0.279 mM, respectively. Furthermore, we put forward a colorimetric method for AMP detection based on nanozyme inhibition. The research on the inhibitory effects of small molecules on nanozymes expands the scope of analysis based on nanozymes and the inhibition mechanism study may offer some insight into investigating the interaction between nanozymes and inhibitors.

Topics & Concepts

ChemistryDrugCombinatorial chemistryOxidase testAtom (system on chip)BiophysicsNanotechnologyBiochemistryPharmacologyEnzymeMaterials scienceBiologyComputer scienceEmbedded systemAdvanced Nanomaterials in CatalysisNanocluster Synthesis and ApplicationsAdvanced biosensing and bioanalysis techniques