Rationale design of novel substituted 1,3,5-triazine candidates as dual IDH1(R132H)/ IDH2(R140Q) inhibitors with high selectivity against acute myeloid leukemia: In vitro and in vivo preclinical investigations

Haytham O. Tawfik, Mai H. A. Mousa, Mohamed Y. Zaky, Ahmed M. El‐Dessouki, Marwa Sharaky, Omeima Abdullah, Mervat H. El‐Hamamsy, Ahmed A. Al‐Karmalawy