Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fcγ Receptor Binding
Chiara Orlandi, Daniel Deredge, Krishanu Ray, Neelakshi Gohain, William D. Tolbert, Anthony L. DeVico, Patrick L. Wintrode, Marzena Pazgier, George K. Lewis
Topics & Concepts
Allosteric regulationEffectorAntigenFc receptorCell biologyReceptorAntibodyBiologyChemistryBiochemistryImmunologyMonoclonal and Polyclonal Antibodies ResearchGlycosylation and Glycoproteins ResearchProtein purification and stability