The role and mechanism of HIF-1α-mediated glypican-3 secretion in hypoxia-induced tumor progression in hepatocellular carcinoma
Pingfeng Wang, Kun Tong, Ying Li, Xuejie Li, Yuan Zhang, Jiangxue Gu, Panwei Lei, Shirong Yan, Pei Hu
Topics & Concepts
Gene knockdownMicrovesiclesGlypican 3Epithelial–mesenchymal transitionExosomeBiologyCancer researchAngiogenesisDownregulation and upregulationCell biologyCell culturemicroRNAHepatocellular carcinomaGeneticsBiochemistryGeneExtracellular vesicles in diseaseAngiogenesis and VEGF in CancerCaveolin-1 and cellular processes