A mechanically tough and ultra-swellable microneedle for acute gout arthritis
Suping Jiang, Wen Wang, Jiming Ke, Shan Huang, Jie Wang, Chengxi Luo, Xiaoxia Li, K. Zhang, Huanhuan Liu, Wensheng Zheng, Jiwen Zhang, Can Peng
Abstract
through down-regulated inflammatory responses such as related cytokines IL-1β, IL-6, and TNF-α. These results demonstrated that the mechanically tough and super-swelling HMNs could be a promising tool for effective Col delivery to relieve AGA.
Topics & Concepts
GoutColchicinePhotopolymerBiomedical engineeringChemistryDiffusionMaterials scienceNanotechnologyMedicineComposite materialPolymerInternal medicineBiochemistryPolymerizationPhysicsThermodynamicsAdvancements in Transdermal Drug DeliveryToxin Mechanisms and ImmunotoxinsDermatology and Skin Diseases