Dosing algorithm for Tacrolimus in Tunisian Kidney transplant patients: Effect of CYP 3A4*1B and CYP3A4*22 polymorphisms
Nadia Ben-Fredj, Ibtissem Hannachi, Zohra Chadli, Haifa Ben-Romdhane, Naceur A. Boughattas, Najah Ben-Fadhel, Karim Aouam
Topics & Concepts
CYP3A5TacrolimusQuartileMedicineDosingTrough levelTrough ConcentrationPopulationKidney transplantationPharmacogeneticsCYP3A4Therapeutic indexUrologyKidney transplantInternal medicineGenotypePharmacologyKidneyAlgorithmTransplantationBiologyMathematicsConfidence intervalDrugGeneticsCytochrome P450GeneEnvironmental healthMetabolismRenal Transplantation Outcomes and TreatmentsPharmacological Effects and Toxicity StudiesHIV/AIDS drug development and treatment