Per- and polyfluoroalkyl substances (PFAS) inhibit cytochrome P450 CYP3A7 through direct coordination to the heme iron and water displacement
Michaela Hvizdak, Sylvie E. Kandel, Hannah M. Work, Emily G. Gracey, Rebecca L. McCullough, Jed N. Lampe
Topics & Concepts
ChemistryEstriolCytochrome P450BiochemistryInternal medicineMetabolismHormoneMedicinePer- and polyfluoroalkyl substances researchToxic Organic Pollutants ImpactEffects and risks of endocrine disrupting chemicals