Design, synthesis and biological activity evaluation of novel carbazole-benzylpiperidine hybrids as potential anti Alzheimer agents
Batool Sadeghian, Amirhossein Sakhteman, Zeinab Faghih, Hamid Nadri, Najmeh Edraki, Aida Iraji, Issa Sadeghian, Zahra Rezaei
Topics & Concepts
ButyrylcholinesteraseAcetylcholinesteraseChemistryDocking (animal)IC50CarbazoleAchéStereochemistryCombinatorial chemistryInhibitory postsynaptic potentialActive siteLigand (biochemistry)EnzymeBiochemistryIn vitroReceptorOrganic chemistryNeurosciencePsychologyNursingMedicineCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsMedicinal Plants and Neuroprotection