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Synthesis, preclinical evaluation and pilot clinical translation of [68Ga]Ga-PMD22, a novel nanobody PET probe targeting CLDN18.2 of gastrointestinal cancer

Rongxi Wang, Zhidong Bai, Wentao Zhong, Chenzhen Li, Jiarou Wang, Jialin Xiang, Junfeng Du, Bing Jia, Zhaohui Zhu

2024European Journal of Nuclear Medicine and Molecular Imaging16 citationsDOI

Topics & Concepts

Translation (biology)MedicineCancerCancer researchMedical physicsNuclear medicineInternal medicineChemistryMessenger RNABiochemistryGeneRadiopharmaceutical Chemistry and ApplicationsPeptidase Inhibition and AnalysisMonoclonal and Polyclonal Antibodies Research
Synthesis, preclinical evaluation and pilot clinical translation of [68Ga]Ga-PMD22, a novel nanobody PET probe targeting CLDN18.2 of gastrointestinal cancer | Litcius