Three's a crowd – stabilisation, structure, and applications of DNA triplexes
Maria Dalla Pozza, Ahmad Abdullrahman, Christine J. Cardin, Gilles Gasser, J.P. Hall
Abstract
degradation, is essential - these areas will be discussed in this review. Ruthenium polypyridyl complexes, which are able to photooxidise DNA and act as luminescent DNA probes, may serve as a suitable photophysical payload for a TFO system and the developments in this area in the context of DNA triplexes will also be reviewed.
Topics & Concepts
OligonucleotideDNADuplex (building)Computational biologyGroove (engineering)Minor grooveBiophysicsChemistryNanotechnologyCombinatorial chemistryBiologyMaterials scienceBiochemistryMetallurgyDNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniquesMetal complexes synthesis and properties