Litcius/Paper detail

The Role of Probiotics in Cancer Prevention

Katarzyna Śliżewska, Paulina Markowiak‐Kopeć, Weronika Śliżewska

2020Cancers274 citationsDOIOpen Access PDF

Abstract

The gut microbiome can play important role in maintaining homeostasis in the human body. An imbalance in the gut microbiome can lead to pro-inflammatory immune responses and the initiation of disease processes, including cancer. The research results prove some strains of probiotics by modulating intestinal microbiota and immune response can be used for cancer prevention or/and as adjuvant treatment during anticancer chemotherapy. This review presents the latest advances in research into the effectiveness of probiotics in the prevention and treatment support of cancer. The described issues concern to the anticancer activity of probiotic microorganisms and their metabolites. In addition, we described the potential mechanisms of probiotic chemoprevention and the advisability of using probiotics.

Topics & Concepts

ProbioticImmune systemMicrobiomeCancerCancer preventionDiseaseAdjuvantMedicineGut microbiomeImmunologyColorectal cancerGut floraBioinformaticsBiologyInternal medicineBacteriaGeneticsProbiotics and Fermented FoodsGut microbiota and healthDigestive system and related health