Catalytic site-specific and regioselective (3 + 2) transannulations between 1,2,3-thiadiazoles and allenoates
Cunzhi Chen, Shuyan Fang, Mingwu Yu, Jiaxi Xu, Zhanhui Yang
Abstract
Catalytic transannulations between perpendicularly strained allenoates and 1,2,3-thiadiazoles produce tetrasubstituted thiophenes, site-specifically and regioselectively.
Topics & Concepts
ThiadiazolesRegioselectivityChemistryCatalysisMedicinal chemistryOrganic chemistryCyclopropane Reaction MechanismsCatalytic Alkyne ReactionsClick Chemistry and Applications