PM2.5 induces mitochondrial dysfunction via AHR-mediated cyp1a1 overexpression during zebrafish heart development
Jin Chen, Mingxuan Zhang, Hongmei Zou, Stanley Aniagu, Yan Jiang, Tao Chen, Tao Chen
Topics & Concepts
Mitochondrial ROSMitochondrial permeability transition poreMitochondrionMPTPZebrafishCell biologyAryl hydrocarbon receptorGene knockdownReactive oxygen speciesApoptosisPINK1BiologyOxidative stressInner mitochondrial membraneMitophagyChemistryProgrammed cell deathBiochemistryEndocrinologyAutophagyTranscription factorDopaminergicDopamineGeneAir Quality and Health ImpactsBirth, Development, and HealthEnergy and Environment Impacts