Inverting glucuronidation of hymecromone <i>in situ</i> by catalytic nanocompartments
Maria Korpidou, Viviana Maffeis, Ionel Adrian Dinu, Cora‐Ann Schoenenberger, Wolfgang Meier, Cornelia G. Palivan
Abstract
over 24 hours. Such catalytic platforms, which locally revert a drug metabolite into its active form, open new avenues in the design of therapeutics that aim at prolonging the residence time of a drug.
Topics & Concepts
In situGlucuronidationCatalysisMaterials scienceChemistryOrganic chemistryMicrosomeEnzymePorphyrin and Phthalocyanine ChemistrySupramolecular Chemistry and ComplexesMolecular Sensors and Ion Detection