Engineered Extracellular Vesicles as a New Class of Nanomedicine
Xiaowei Wen, Zerun Hao, Haofan Yin, Jie Min, Xueying Wang, Sihan Sun, Gang Ruan
Abstract
imaging of EVs, the mechanistic understandings, and the clinical translation aspects are discussed. The discussion is primarily on preclinical studies while briefly mentioning the clinical trials. With continued interdisciplinary research efforts from biologists, pharmacists, physicians, bioengineers, and chemical engineers, engineered EVs could become a powerful solution for many major diseases such as neurological, immunological, and cardiovascular diseases.
Topics & Concepts
NanomedicineExtracellular vesiclesTranslational researchNanotechnologyMedicineBiologyPathologyMaterials scienceNanoparticleCell biologyExtracellular vesicles in diseaseMicroRNA in disease regulationRNA Interference and Gene Delivery