Synthesis of 1-perfluoroalkyl-3-heteroaryl bicyclo[1.1.1]pentanes <i>via</i> visible light-induced and metal-free perfluoroalkylation of [1.1.1]propellane
Boan Yan, Gongcheng Xu, Hang Han, Jun Hong, Wenhao Xu, Deyou Lan, Chuanming Yu, Xinpeng Jiang
Abstract
Visible light-induced perfluoroalkylation of [1.1.1]propellane provides a sustainable way to incorporate perfluoroalkyl-substituted BCPs into various heterocycles.
Topics & Concepts
PropellaneBicyclic moleculeChemistryPhotochemistryComputational chemistryCombinatorial chemistryStereochemistryFluorine in Organic ChemistryRadical Photochemical ReactionsSulfur-Based Synthesis Techniques