Cyclical administration of corticosterone results in aggravation of depression-like behaviors and accompanying downregulations in reelin in an animal model of chronic stress relevant to human recurrent depression
K. A. Lebedeva, Josh Allen, Erin Y. Kulhawy, Héctor J. Caruncho, Lisa E. Kalynchuk
Topics & Concepts
Behavioural despair testCorticosteroneDentate gyrusPsychologyNeurochemicalOpen fieldDepression (economics)HippocampusChronic stressNeuroplasticityGlucocorticoidReelinNeuroscienceInternal medicineAnimal models of depressionEndocrinologyMedicinePsychiatryAntidepressantHormoneReceptorEconomicsMacroeconomicsStress Responses and CortisolTryptophan and brain disordersNeurogenesis and neuroplasticity mechanisms