NRF2 participates in the suppressive tumor immune microenvironment of KRAS/KEAP1 co-mutant non-small cell lung cancer by inhibiting the STING pathway
Sun Xiaodan, Peiyan Zhao, Hui Li, Yan Liu, Cheng Ying
Topics & Concepts
KRASCancer researchTumor microenvironmentStingMutantImmune systemLung cancerCancerMedicineBiologyImmunologyTumor cellsOncologyInternal medicineGeneGeneticsColorectal cancerEngineeringAerospace engineeringinterferon and immune responsesRNA modifications and cancerUbiquitin and proteasome pathways