Diagnostic and Treatment Strategies for AL Amyloidosis in an Era of Therapeutic Innovation
Danai Dima, Sandra Mazzoni, Faiz Anwer, Jack Khouri, Christy Samaras, Jason Valent, Louis Williams
Abstract
Despite significant progress and improving outcomes in the management of plasma cell disorders, AL amyloidosis remains diagnostically and therapeutically challenging for clinicians across practice settings. There is, however, a reason for optimism with the advent of new combination therapy approaches and novel targets offering the promise of improvement in end organ function, survival, and quality of life. This review offers a clinically applicable overview of an approach to diagnosis, risk stratification, and clinical management of AL amyloidosis in an era of rapid therapeutic innovation.
Topics & Concepts
AmyloidosisIntensive care medicineMedicineOptimismClinical PracticeRisk stratificationQuality of life (healthcare)Internal medicinePsychologyPhysical therapyPsychotherapistNursingAmyloidosis: Diagnosis, Treatment, OutcomesParathyroid Disorders and TreatmentsNeuroendocrine Tumor Research Advances