WT1<sup>+</sup> glomerular parietal epithelial progenitors promote renal proximal tubule regeneration after severe acute kidney injury
Xizhen Hong, Hao Nie, Juan Deng, Shiting Liang, Liting Chen, Jing Li, Siqiao Gong, Guobao Wang, Wei Zuo, Fan Fan Hou, Fujian Zhang
Abstract
PECs that promote renal proximal tubule regeneration/repair after severe AKI, and the expression of WT1 in PECs and PTECs is essential for renal proximal tubule regeneration after severe kidney injury.
Topics & Concepts
Acute kidney injuryKidneyRegeneration (biology)Renal stem cellProgenitor cellCancer researchStem cellBiologyPathologyProximal tubuleCell biologyMedicineInternal medicineRenal and related cancersOrgan Donation and TransplantationRenal cell carcinoma treatment