Structure-based designing and synthesis of 2-phenylchromone derivatives as potent tyrosinase inhibitors: In vitro and in silico studies
Jamshaid Ashraf, Ehsan Ullah Mughal, Reem I. Alsantali, Rami J. Obaid, Amina Sadiq, Nafeesa Naeem, Anser Ali, Anam Massadaq, Qamar Javed, Asif Javid, Sajjad Hussain Sumrra, Muhammad Naveed Zafar, Saleh A. Ahmed
Topics & Concepts
ChemistryIn silicoTyrosinaseIn vitroStereochemistryStructure–activity relationshipMolecular modelChemical synthesisCombinatorial chemistryBiochemistryComputational biologyEnzymeGeneBiologymelanin and skin pigmentationBiochemical Analysis and Sensing TechniquesBioactive Compounds and Antitumor Agents