Litcius/Paper detail

How do we address neglected sulfur pharmacophores in drug discovery?

Michael J. Tilby, Michael C. Willis

2021Expert Opinion on Drug Discovery131 citationsDOIOpen Access PDF

Abstract

Sulfur is an ubiquitous heteroatom in medicinal chemistry [1]. Its prevalence is often credited to its ability to exist in many oxidation states, whilst also being capable of bonding to a variety o...

Topics & Concepts

Drug discoveryPharmacophoreDrugComputational biologyComputer sciencePharmacologyChemistryMedicineBiologyBioinformaticsSulfur-Based Synthesis TechniquesSynthesis and Catalytic ReactionsClick Chemistry and Applications