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Water-soluble copper pyrithione complexes with cytotoxic and antibacterial activity

Atreyee Mishra, Karrera Y. Djoko, Yi‐Hsuan Lee, Rianne M. Lord, Grace Kaul, Abdul Akhir, Deepanshi Saxena, Sidharth Chopra, James W. Walton

2023Organic & Biomolecular Chemistry13 citationsDOIOpen Access PDF

Abstract

Novel PEGylated copper pyrithione complexes show high bioactivity in anticancer and antibacterial assays, with enhanced aqueous solubility.

Topics & Concepts

ChemistryCopperAntibacterial activityCytotoxic T cellWater solubleNuclear chemistryCombinatorial chemistryOrganic chemistryBacteriaBiochemistryIn vitroBiologyGeneticsMetal complexes synthesis and propertiesTrace Elements in HealthMolecular Sensors and Ion Detection
Water-soluble copper pyrithione complexes with cytotoxic and antibacterial activity | Litcius