Crucial Role of ppGpp in the Resilience of Escherichia coli to Growth Disruption
Clément Patacq, Nicolas Chaudet, Fabien Létisse
Abstract
The capacity of microbes to resist and overcome environmental insults, known as resilience, allows them to survive in changing environments but also to resist antibiotic and biocide treatments and immune system responses. Although the role of the stringent response in bacterial resilience to nutritional stresses has been well studied, little is known about its importance in the ability of the bacteria to not just resist but also recover from these disturbances.
Topics & Concepts
Resilience (materials science)ResistBacteriaEscherichia coliBiocideMicrobiologyImmune systemBiologyStringent responseAntibioticsChemistryNanotechnologyBiochemistryGeneticsMaterials scienceOrganic chemistryGeneLayer (electronics)Composite materialBacterial Genetics and BiotechnologyMicrobial Metabolic Engineering and BioproductionEvolution and Genetic Dynamics