Synthetic Biology Approaches for Engineering Next-Generation Adenoviral Gene Therapies
Logan Thrasher Collins, David T. Curiel
Abstract
, providing precise Ad tropisms, and incorporating genetic circuits to make smart therapies which adapt to environmental stimuli. Synthetic biology engineering of Ad vectors may lead to superior gene delivery and editing platforms which could find applications in a wide range of therapeutic contexts.
Topics & Concepts
Synthetic biologyGenetic enhancementComputational biologyViral vectorBiologyModular designGene deliveryComputer scienceNanotechnologyNeuroscienceGeneGeneticsRecombinant DNAMaterials scienceOperating systemCRISPR and Genetic EngineeringVirus-based gene therapy researchViral Infectious Diseases and Gene Expression in Insects