Synthesis, biological evaluation of novel iridium(III) complexes targeting mitochondria toward melanoma B16 cells
Yuhan Yuan, Yuanyuan Zhang, Jing Chen, Chunxia Huang, Haimei Liu, Wenlong Li, Lijuan Liang, Yi Wang, Yunjun Liu
Topics & Concepts
ChemistryIridiumDeprotonationGlutathioneStereochemistryLigand (biochemistry)IntracellularBromideIn vitroCytotoxicityMitochondrionMolecular biologyBiochemistryReceptorOrganic chemistryEnzymeCatalysisIonBiologyQuinazolinone synthesis and applicationsMetal complexes synthesis and propertiesCancer therapeutics and mechanisms