Extracellular Hsp90 of Candida albicans contributes to the virulence of the pathogen by activating the NF-κB signaling pathway and inducing macrophage pyroptosis
Ting Fang, Juan Xiong, Xin Huang, Xinyu Fang, Xuqing Shen, Yuanying Jiang, Hui Lu
Topics & Concepts
BiologyPyroptosisCandida albicansVirulenceExtracellularMacrophageMicrobiologySignal transductionPathogenHsp90Fungal pathogenNF-κBCell biologyHeat shock proteinGeneticsApoptosisGeneProgrammed cell deathIn vitroInflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideHeat shock proteins research