Resveratrol Nanoparticles: A Promising Therapeutic Advancement over Native Resveratrol
Ill‐Min Chung, Umadevi Subramanian, Prabhu Thirupathi, Baskar Venkidasamy, Ramkumar Samynathan, Baniekal Hiremath Gangadhar, Govindasamy Rajakumar, Muthu Thiruvengadam
Abstract
The importance of fruit-derived resveratrol (RES) in the treatment of various diseases has been discussed in various research publications. Those research findings have indicated the ability of the molecule as therapeutic in the context of in vitro and in vivo conditions. Mostly, the application of RES in in vivo conditions, encapsulation processes have been carried out using various nanoparticles that are made of biocompatible biomaterials, which are easily digested or metabolized, and RES is absorbed effectively. These biomaterials are non-toxic and are safe to be used as components in the biotherapeutics. They are made from naturally available by-products of food materials like zein or corn or components of the physiological system as with lipids. The versatility of the RES nanoparticles in their different materials, working range sizes, specificity in their targeting in various human diseases, and the mechanisms associated with them are discussed in this review.