Prevalence and Molecular Epidemiology of Extended-Spectrum-β-Lactamase (ESBL)-Producing <i>Escherichia coli</i> From Multiple Sectors of the Swine Industry in Korea: A Korean Nationwide Monitoring Program for a One Health Approach to Combat Antimicrobial Resistance
Young Ah Kim, Hyunsoo Kim, Young Hee Seo, Go Eun Park, Hyukmin Lee, Kyungwon Lee
Abstract
BACKGROUND: (ESBL-EC) in workers, livestock, and the farm environment in Korea. METHODS: ) genes and antimicrobial resistance were determined. Clonality was evaluated with pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). RESULTS: gene. PFGE was successful for 197 of the 232 isolates, and most PFGE types were heterogeneous, except for some dominant PFGE types (O, R, T, U, and V). MLST of 88 isolates was performed for representative PFGE types; however, no dominant sequence type was observed. CONCLUSIONS: The proportion of ESBL-EC in swine industry-related samples was significant, and the isolates harbored common clinical ESBL gene types. These molecular epidemiologic data could provide important evidence for antimicrobial-resistance control through a one health approach.