Piezo1 activates the NLRP3 inflammasome in nucleus pulposus cell-mediated by Ca2+/NF-κB pathway
Yi Sun, Ping Leng, Mengxiong Song, Dawei Li, Pengcheng Guo, Xipeng Xu, Huanshen Gao, Zhenghui Li, Chenkai Li, Haining Zhang
Topics & Concepts
InflammasomePIEZO1Cell biologyNucleusChemistryInflammationDownregulation and upregulationReceptorBiologyImmunologyIon channelBiochemistryMechanosensitive channelsGeneInflammasome and immune disordersErythrocyte Function and PathophysiologyHereditary Neurological Disorders