Anlotinib may enhance the efficacy of anti-PD1 therapy by inhibiting the AKT pathway and promoting the apoptosis of CAFs in lung adenocarcinoma
Hui Tang, Tingting You, Hui Ge, Jingxi Gao, Yingyi Wang, Chunmei Bai, Zhao Sun, Qin Han, Robert Chunhua Zhao
Topics & Concepts
Cancer researchTumor microenvironmentApoptosisProtein kinase BLung cancerChemistryMedicineInternal medicineBiochemistryTumor cellsImmune cells in cancerLung Cancer Research StudiesCancer Immunotherapy and Biomarkers