Design and Synthesis of a New Class of Pyridine-Based <i>N</i>-Sulfonamides Exhibiting Antiviral, Antimicrobial, and Enzyme Inhibition Characteristics
Rasha A. Azzam, Rasha E. Elsayed, Galal H. Elgemeie
Abstract
was shown to be the most potent compound among all examined compounds.
Topics & Concepts
AntimicrobialChemistryBenzimidazolePyridineBenzothiazoleDihydrofolate reductaseEnzymeKlebsiella pneumoniaIC50ThiadiazolesStereochemistrySulfonamideCombinatorial chemistryOrganic chemistryBiochemistryIn vitroEscherichia coliGeneQuinazolinone synthesis and applicationsResearch on Leishmaniasis StudiesSynthesis and biological activity