Protein Detection Based on Field-Effect Transistor Biosensors for Diagnosing Diseases
Zhicheng Zhang, Haiyang Li, Ning Zhou, Zhi Zheng, Tianyou Zhai, Fan Xia, Xiaoding Lou
Abstract
Proteins have been one of the most important biomarkers for diagnosing diseases, and field-effect transistor (FET) biosensors possess high sensitivity; are label-free; and feature real-time detection, rapidity, and easy integration for protein detection. FET biosensors are mainly made up of FET parts, such as channel materials, and bio parts, such as receptors. This Tutorial provides an in-depth exploration of FET biosensors for protein detection from the composition perspective and discusses the commercialization of point-of-care diagnostics of proteins based on FET biosensors.
Topics & Concepts
ChemistryBiosensorNanotechnologyField-effect transistorTransistorProtein detectionComputational biologyBiochemical engineeringBiochemistryElectrical engineeringEngineeringVoltageMaterials scienceBiologyNanowire Synthesis and ApplicationsAnalytical Chemistry and SensorsAdvanced biosensing and bioanalysis techniques