Thymoquinone induces oxidative stress-mediated apoptosis through downregulation of Jak2/STAT3 signaling pathway in human melanoma cells
Pawan Kumar Raut, Hui Seong Lee, Sang Hoon Joo, Kyung‐Soo Chun
Topics & Concepts
ThymoquinoneSurvivinSTAT3STAT proteinApoptosisJanus kinase 2Cancer researchSignal transductionChemistryOxidative stressReactive oxygen speciesPharmacologyBiologyBiochemistryAntioxidantNigella sativa pharmacological applicationsBioactive Compounds and Antitumor AgentsPharmacological Effects of Natural Compounds