Pro-Oxidant Therapeutic Activities of Cerium Oxide Nanoparticles in Colorectal Carcinoma Cells
Aparna Datta, Snehasis Mishra, Krishnendu Manna, Krishna Das Saha, Siddhartha Mukherjee, Somenath Roy
Abstract
treatment causes DNA fragmentation through enhanced generation of ROS, which ultimately leads to cellular apoptosis through the p53-dependent mitochondrial signaling pathway.
Topics & Concepts
ApoptosisReactive oxygen speciesChemistryAnnexinFlow cytometryCell cultureHEK 293 cellsCell biologyCytochrome cMolecular biologyBiochemistryBiologyReceptorGeneticsAdvanced Nanomaterials in CatalysisNanocluster Synthesis and ApplicationsNanoparticles: synthesis and applications