A Ni-catalyzed asymmetric C(sp)–P cross-coupling reaction for the synthesis of P-stereogenic alkynylphosphines
Bin Zhang, Wenqing Zhou, Xu-Teng Liu, Yingying Sun, Qing‐Wei Zhang
Abstract
A catalytic asymmetric C(sp)–P cross coupling reaction for the synthesis of P-stereogenic alkynylphosphines was realized. A series of alkynylphosphines which could be derivatized to useful phosphine compounds was synthesized with excellent enantioselectivities.
Topics & Concepts
StereocenterCatalysisCoupling reactionChemistryCoupling (piping)StereochemistryEnantioselective synthesisMaterials scienceOrganic chemistryMetallurgyAsymmetric Hydrogenation and CatalysisCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling Reactions