New pyrimidine and pyrazole-based compounds as potential EGFR inhibitors: Synthesis, anticancer, antimicrobial evaluation and computational studies
Ismail M. M. Othman, Zahra M. Al-Amshany, Nada Y. Tashkandi, Mohamed A. M. Gad‐Elkareem, Manal M. Anwar, Eman S. Nossier
Topics & Concepts
ErlotinibChemistryAntimicrobialDocking (animal)PharmacologyEGFR inhibitorsPyrazolePyrimidineIn vitroIn silicoEpidermal growth factor receptorBiochemistryStereochemistryReceptorMedicineOrganic chemistryNursingGeneLung Cancer Treatments and MutationsSynthesis and biological activityCancer therapeutics and mechanisms