Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products
Nathaniel C. Gilbert, Jana Gerstmeier, Erin Schexnaydre, Friedemann Börner, Ulrike Garscha, David B. Neau, Oliver Werz, Marcia E. Newcomer
Topics & Concepts
Allosteric regulationNordihydroguaiaretic acidLipoxygenaseActive siteChemistryEnzymeBiochemistryArachidonate 5-lipoxygenaseStereochemistryArachidonic acidPharmacological Effects of Medicinal PlantsNatural product bioactivities and synthesis