NCAPD2 inhibits autophagy by regulating Ca2+/CAMKK2/AMPK/mTORC1 pathway and PARP-1/SIRT1 axis to promote colorectal cancer
Zuolei Jing, Xinyuan He, Zhirong Jia, Yunli Sa, Bolin Yang, Ping Liu
Topics & Concepts
mTORC1AutophagyAMPKColorectal cancerCancer researchCell biologyPI3K/AKT/mTOR pathwayBiologyCancerKinaseSignal transductionGeneticsProtein kinase AApoptosisAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and DiseaseUbiquitin and proteasome pathways